Tuesday, March 5, 2013

Morning light at Termini. #rome #italy #trains

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Source: http://wallofdis.tumblr.com/post/44610264722

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S.Africa postpones hearing for murder-accused policemen

JOHANNESBURG (Reuters) - The case against eight South African policemen accused of murder after shackling a man to the back of a police vehicle and dragging him to a nearby station was postponed on Monday pending a formal identification parade.

The policemen were not present in the packed Benoni courtroom in east Johannesburg. The case, which has made international headlines, will resume on Friday, the magistrate ordered. The men will be held in custody in the interim.

Video footage captured by an onlooker last week of policemen tying Mozambican taxi driver Mido Macia, 27, to the back of a police vehicle and driving off through the busy streets shocked South Africans.

It also reinforced the police's reputation for brutality, corruption and incompetence in a country where more than three people die in police custody every day.

About 100 protesters gathered outside the court, some carrying posters saying "No bail for police killers".

"In South Africa we are having a big problem with the police. You see them and you run away because you cannot trust them," said Sifiso Mlotshwa, one of scores of demonstrating taxi drivers.

The incident came a week after the main detective in the murder case against Olympic star Oscar Pistorius was removed from the investigation when it emerged he was facing attempted murder charges for allegedly opening fire on a minibus full of passengers. .

Source: http://news.yahoo.com/africa-postpones-hearing-murder-accused-policemen-092731555.html

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Monday, March 4, 2013

Ark. Gov. Beebe vetoes 12-week abortion ban

Arkansas Gov. Mike Beebe is interviewed in a hallway at the Arkansas state Capitol in Little Rock, Ark., Monday, March 4, 2013, after vetoing legislation that would have banned abortions 12 weeks into a pregnancy. (AP Photo/Danny Johnston)

Arkansas Gov. Mike Beebe is interviewed in a hallway at the Arkansas state Capitol in Little Rock, Ark., Monday, March 4, 2013, after vetoing legislation that would have banned abortions 12 weeks into a pregnancy. (AP Photo/Danny Johnston)

FILE - In this Feb. 19, 2013, file photo, Sen. Jason Rapert, R-Conway, speaks to a reporter after a meeting of the House Committee on Public Health, Welfare and Labor at the Arkansas state Capitol in Little Rock, Ark., where his bill dealing with abortion received the committee's recommendation. Arkansas Gov. Mike Beebe on Monday, March 4, vetoed the legislation by Rapert that would have banned abortions 12 weeks into a pregnancy. (AP Photo/Danny Johnston, File)

In this photo taken Feb. 19, 2013, Sen. Jason Rapert, R-Conway, is interviewed after a meeting of the House Committee on Public Health, Welfare and Labor at the Arkansas state Capitol in Little Rock, Ark. Arkansas Gov. Mike Beebe on Monday, March 4, vetoed legislation by Rapert that would have banned abortions 12 weeks into a pregnancy. (AP Photo/Danny Johnston)

LITTLE ROCK, Ark. (AP) ? Arkansas Gov. Mike Beebe on Monday vetoed legislation banning most abortions 12 weeks into pregnancy, rejecting what opponents said would be the most restrictive restriction in the U.S.

The legislation would ban the procedure at 12 weeks if a fetal heartbeat is detected using an abdominal ultrasound. The Democratic governor's veto come less than a week after the state enacted a 20-week ban. That restriction went into effect after the Legislature overrode another veto by Beebe.

Beebe's objections to the 12-week ban echoed those he had to the 20-week ban. He said the 12-week ban contradicts the U.S. Supreme Court's 1973 Roe v. Wade decision that legalized abortion until a fetus could survive outside the womb. A fetus is generally considered viable at 22 to 24 weeks.

"Because it would impose a ban on a woman's right to choose an elective, nontherapeutic abortion well before viability, Senate Bill 134 blatantly contradicts the United States Constitution, as interpreted by the Supreme Court," Beebe said in his veto letter. "When I was sworn in as governor I took an oath to preserve, protect and defend both the Arkansas Constitution and the Constitution of the United States. I take that oath seriously."

The Republican-led Legislature approved the measure last week. The sponsor said he would ask the Senate to override Beebe's veto of the 12-week ban on Tuesday. It takes a simple majority of the House and Senate to override a governor's veto. Republicans hold 21 of the 35 Senate seats and 51 of the 100 House seats.

"I'm disappointed for all of the unborn children that could have been saved in this bill, but I have faith that the 70 percent of the Legislature that voted to pass the bill will be there to override this veto," Sen. Jason Rapert, a Republican from Conway, told reporters after the veto was announced on the Senate floor.

Beebe had previously said he found the 12-week ban even more problematic than the 20-week one. He wouldn't say whether rejecting the 12-week ban was an easier decision.

"Both of them are constitutional issues. I don't know if you'd characterize one as easier than the other," Beebe told reporters after issuing his veto. "It becomes a question of what is the constitutionality of the bill."

The 12-week measure includes exemptions for rape, incest, the life of the mother and highly lethal fetal disorders. The original version of Rapert's bill would have banned abortions as early as six weeks into a pregnancy, but he changed the measure after facing resistance from some lawmakers.

Beebe said he did not plan on reaching out to lawmakers in the House or Senate to ask them to uphold his veto. At least one Democrat who voted for Rapert's bill said he would likely oppose overriding the governor's veto.

"I can't imagine I'll vote to override it," said Sen. Larry Teague, a Democrat from Nashville. "I think it's probably less constitutional than the first one was."

No Democrats voted in the Senate to override Beebe's veto of the 20-week measure last week, and only two of the 48 House Democrats supported the override.

The Senate approved the ban on a 26-8 vote Thursday moments after approving the override of the 20-week prohibition along party lines. The House approved it a week earlier on a 68-20 vote.

The measures are among several abortion restrictions Arkansas lawmakers are considering after Republicans won control of the House and Senate in November.

The American Civil Liberties Union of Arkansas has vowed to sue to overturn the 12-week ban if it's enacted.

"Despite continued attacks on women's health care from the Arkansas Legislature, Gov. Beebe has remained steadfast in his support for women's health care," said Jill June, president and CEO of Planned Parenthood of the Heartland. "Unfortunately we can't say the same about extreme lawmakers pushing these dangerous bills."

If lawmakers override Beebe's veto, the 12-week ban would take effect 90 days after the Legislature adjourns. The Legislature is not expected to adjourn until later this month or next month.

The 20-week ban took effect immediately.

___

Andrew DeMillo can be reached at www.twitter.com/ademillo

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/bbd825583c8542898e6fa7d440b9febc/Article_2013-03-04-US-XGR-Arkansas-Legislature-Abortion/id-bacbfb7584ea404c8ad0b568fd8b49b0

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Rogers, founder of Motown group The Miracles, dies

FILE - In this March 20, 2009 file photo, members of the Motown group The Miracles, from left: William "Smokey" Robinson, Warren "Pete" Moore, Claudette Robinson, and Robert "Bobby" Rogers, are honored with a star on the Hollywood Walk of Fame in Los Angeles. Rogers, a founding member of the group and a collaborator with Smokey, has died. Motown Museum board member Allen Rawls said Rogers died Sunday, March 3, 2013, at his home. He was 73. (AP Photo/Damian Dovarganes, file)

FILE - In this March 20, 2009 file photo, members of the Motown group The Miracles, from left: William "Smokey" Robinson, Warren "Pete" Moore, Claudette Robinson, and Robert "Bobby" Rogers, are honored with a star on the Hollywood Walk of Fame in Los Angeles. Rogers, a founding member of the group and a collaborator with Smokey, has died. Motown Museum board member Allen Rawls said Rogers died Sunday, March 3, 2013, at his home. He was 73. (AP Photo/Damian Dovarganes, file)

FILE - This 2009 file photo, shows Bobby Rogers, a founding member of the Miracles, in Detroit. Rogers, a collaborator with Smokey Robinson, has died. Motown Museum board member Allen Rawls said Rogers died Sunday, March 3, 2013, at his home. He was 73. Rogers and The Miracles were inducted into the Rock and Roll Hall of Fame in 2012. (AP Photo/The Detroit News, Todd McInturf) DETROIT FREE PRESS OUT; HUFFINGTON POST OUT.

(AP) ? Bobby Rogers, a founding member of Motown group The Miracles and a songwriting collaborator with Smokey Robinson, died Sunday at his suburban Detroit home. He was 73.

Motown Museum board member Allen Rawls said Rogers died about 6 a.m. in Southfield. Rogers had been ill for several years.

Rogers formed the group in 1956 with cousin Claudette Rogers, Pete Moore, Ronnie White and Robinson. Their hits included "Shop Around," ''You've Really Got a Hold on Me," ''The Tracks of My Tears," ''Going to a Go-Go," ''I Second That Emotion" and "The Tears of a Clown."

"Another soldier in my life has fallen. Bobby Rogers was my brother and a really good friend," Robinson said Sunday in a statement. "He and I were born on the exact same day in the same hospital in Detroit. I am really going to miss him. I loved him very much."

Roger's cousin Claudette told the Detroit Free Press that everyone was drawn to his personality.

"People always commented on the tall one with the glasses," she said. "He was personable, approachable and he loved talking to the women, loved talking to the guys, loved to dance, loved to sing, loved to perform. That was the joy of his life."

His voice can be heard on Marvin Gaye's "What's Going On," with Rogers saying, "It's just a groovy party, man, I can dig it." Mary Wilson of the Supremes said that captured his essence.

"If people want to remember him, they should put that record on and listen to Bobby," Wilson told the newspaper. "That's who he was."

Rogers and The Miracles were inducted into the Rock and Roll Hall of Fame in 2012. He was too ill to attend the ceremony.

He shared songwriting credits with Robinson on The Temptations' "The Way You Do the Things You Do," The Contours' "First I Look at the Purse" and The Miracles' "Going to a Go-Go."

Funeral arrangements through James H. Cole Home for Funerals in Detroit were incomplete Sunday afternoon.

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/3d281c11a96b4ad082fe88aa0db04305/Article_2013-03-03-Obit-Bobby%20Rogers/id-9329e9f681824aa399087baf4df983e1

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Two new genes linked to amyotrophic lateral sclerosis (ALS) and related disorders

Mar. 3, 2013 ? A study led by St. Jude Children's Research Hospital has discovered mutations in two genes that lead to the death of nerve cells in amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, and related degenerative diseases.

The same mutation occurred in both genes and led to the abnormal build-up of the proteins inside cells. These proteins play an essential role in normal RNA functioning and have also been linked to cancer, including the Ewing sarcoma, the second most common type of bone cancer in children and adolescents. The finding is the latest in a series of discoveries suggesting degenerative diseases and cancer may have common origins. RNA is the molecule that directs protein assembly based on instructions carried in DNA.

The study also adds to evidence that seemingly unrelated neurodegenerative diseases may involve similar defects in RNA metabolism. Researchers linked the problems to a specific region of the mutated proteins whose normal function was unclear. The study was published today in the advanced online edition of the scientific journal Nature.

"I hope this study helps to build the foundation for desperately needed treatments for ALS and perhaps a broad range of diseases caused by abnormal RNA metabolism," said J. Paul Taylor, M.D., Ph.D., an associate member of the St. Jude Department of Developmental Neurobiology and senior author of the study. Taylor and James Shorter, Ph.D., an assistant professor in the biochemistry and biophysics department at the University of Pennsylvania's Perelman School of Medicine, are the study's corresponding authors.

Each year approximately 5,600 people in the U.S. are found to have ALS. The disease is nearly always fatal, often within five years. Patients suffer muscle wasting and paralysis that affects their limbs and trunk as well as their ability to talk, swallow and breathe. There is no cure.

For this project, St. Jude sequenced just the portion of the genome called the exome, which carries instructions for making proteins. Researchers sequenced the exomes of two families affected by rare inherited degenerative disorders that target cells in the muscle, bone and brain. Neither family carried mutations previously tied to ALS or related diseases. The project built on the infrastructure developed by the St. Jude Children's Research Hospital -- Washington University Pediatric Cancer Genome Project, which played an important role in finding the mutations.

Researchers found the families carried a single, previously unknown mutation in a pair of RNA-binding proteins named hnRNPA2B1 and hnRNPA1. The proteins both bind RNA and help regulate its function. When researchers checked for the same mutations in 517 ALS patients they found hnRNPA1 protein mutated in two patients. One patient had the inherited form of ALS. The other ALS patient had no family history of the disease.

The new mutations occurred in a region of the proteins Taylor refers to as a prion-like domain because it has similarities with yeast proteins called prions. Prions are proteins that can alternate between shapes as needed for different functions. "Until recently we did not know these domains existed in humans and now we realize that hundreds of human proteins have them," Taylor said. "We're only beginning to understand their function in human cells."

Researchers showed the prion-like domains are responsible for the shape change that occurs when these proteins convert into slender threads called fibrils. The mutations accelerate fibril formation and recruit normal proteins to form fibrils. This phenomenon called propagation may explain how ALS and related diseases spread throughout the nervous system.

Taylor speculated that the normal function of prion-like domains is to assemble RNAs into temporary structures called granules, which are part of the cell's normal protein production machinery. Granules are normally short lived, and the RNA-binding proteins involved in their formation are recycled. But in cells with hnRNPA2B1 or hnRNPA1 mutation, RNA granules accumulated in the cytoplasm instead of being disassembled. "That's bad news for RNA regulation, which is bad news for those cells," Taylor said.

The study has several important implications, Taylor said. Recognition that the mutations adversely impact regulation of RNA could lead to targeted therapy to correct the problem. The mutation's location in the prion-like domain might also prove significant. Although the mutations in hnRNPA2B1 or hnRNPA1 appear to be rare, hundreds of other RNA-binding proteins have prion-like domains. Taylor said patients with unexplained neurodegenerative diseases may have mutations in these proteins.

The study's first authors are Hong Joo Kim, Nam Chul Kim, Yong-Dong Wang and Jennifer Moore, all of St. Jude; and Emily Scarborough and Zamia Diaz, both of the University of Pennsylvania. The other authors are Kyle MacLea and Eric Ross, both of Colorado State University; Brian Freibaum, Songqing Li, Amandine Molliex, Anderson Kanagaraj and Robert Carter, all of St. Jude; Kevin Boylan, Aleksandra Wojtas and Rosa Rademakers, all of the Mayo Clinic, Jacksonville, Fla.; Jack Pinkus and Steven Greenberg, both of Brigham and Women's Hospital and Harvard Medical School; John Trojanowski, Bradley Smith, Yun Li and Alice Flynn Ford, all of the University of Pennsylvania; Bryan Traynor, of the National Institute of Aging, National Institutes of Health, Bethesda, Md.; Simon Topp, Athina-Soragia Gkazi, Jack Miller and Christopher Shaw, all of the Institute of Psychiatry, London; Michael Kottlors and Janbernd Kirschner, both of University Children's Hospital Freiburg, Germany; Alan Pestronk and Conrad Weihl, both of the Washington University School of Medicine, St. Louis; Aaron Gitler, Stanford University School of Medicine; Michael Benatar, University of Miami Miller School of Medicine; Oliver King, Boston Biomedical Research Institute, Watertown, Mass.; and Virginia Kimonis, University of California-Irvine.

The research was supported in part by the Packard Foundation, by grants (NS053825, AG032953, DP2OD002177 and NS067354) from the National Institutes of Health, the ALS Association, the Ellison Medical Foundation, a grant (MCB-1023771) from the National Science Foundation and ALSAC.

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The above story is reprinted from materials provided by St. Jude Children's Research Hospital.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Hong Joo Kim, Nam Chul Kim, Yong-Dong Wang, Emily A. Scarborough, Jennifer Moore, Zamia Diaz, Kyle S. MacLea, Brian Freibaum, Songqing Li, Amandine Molliex, Anderson P. Kanagaraj, Robert Carter, Kevin B. Boylan, Aleksandra M. Wojtas, Rosa Rademakers, Jack L. Pinkus, Steven A. Greenberg, John Q. Trojanowski, Bryan J. Traynor, Bradley N. Smith, Simon Topp, Athina-Soragia Gkazi, Jack Miller, Christopher E. Shaw, Michael Kottlors, Janbernd Kirschner, Alan Pestronk, Yun R. Li, Alice Flynn Ford, Aaron D. Gitler, Michael Benatar, Oliver D. King, Virginia E. Kimonis, Eric D. Ross, Conrad C. Weihl, James Shorter, J. Paul Taylor. Mutations in prion-like domains in hnRNPA2B1 and hnRNPA1 cause multisystem proteinopathy and ALS. Nature, 2013; DOI: 10.1038/nature11922

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/pOZEz9hUe_o/130303154857.htm

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Literary Agent ? Creative Writing Tips | Writing and Speaking Tips

This is made difficult by the necessity to write in verse.

First, write a poem in the first person point of view. You must say ?I? did that, this, or the other thing, not ?He?. Show what you felt, said, saw, thought, wished, did, (saying ?I? did it). Make yourself sound entertaining to yourself as your first reader. Surprise yourself. Make yourself sound noble, or else unjustly put upon. And there you sound like a Protagonist. Remember, a poem is always telling a story. Thus, a character is part of the requirements.

You may also create yourself as a cross, petty, treacherous, cruel, corrupt character. To avoid authorial intrusion, you can switch the POV (point of view) to the third person. To flesh out a character fully, it is always proper to be omniscient in telling the story. An antagonist may have plans to thwart and obstruct another character in quest of love, glory, honor, or whatever that character logically desire and deserve. Writing it in other POV?s will make the protagonist appear bias. However, homely protagonists rarely work in poetry.

Do not forget the elements of poetry. Figures of speech are the basic elements. It?s a good idea, let?s say, to have somebody get in bed with someone else. Set your place in a parked car, broom closet, bathtub, something like that, though a bed will do better for romantic touch. To pull off an erotic touch in a poem, make sure you include the senses which make everything erotic and sensual. Bear witness to the scent and sound of the environment wherein the action happened, and do not forget the body language.

Change the point of view to the second person. This is to keep the reader from getting bored with what the omniscient speaker saw in a parked car. Use your imagination. You may say ?I? did that, this, or the other thing and prove it was not in a parked car. But let?s face it: if you?ve really had it in a parked car, you wouldn?t be wasting your time trying to figure out the scent of vehicle emission or the air vent. Or you wouldn?t be wasting your day trying to write a poem. Horace says that one should write the feelings after some moment of tranquility. So don?t write a poem after getting it on in a parked car.

When you have finished showing (not telling) what you did or wished you?d done that night, type ?first draft? neatly in the center of the page and take a glass of water. Now you will want to let someone else read what you?ve written. Most likely, however, your reader will say one of two things: ?I think you need a new printer,? or: ?Who was that you were with in that parked car??

Why don?t you just keep the draft and drink another glass of water, and revise it until you can say you have written a poem. No one will know, but who cares, Emily Dickinson got famous after her publishers discovered hundreds of poems in her room after her death.

Source: http://www.writingspeakingtips.com/literary-agent-creative-writing-tips/

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Sunday, March 3, 2013

Lake Placid Metro Girl's Adjustable Figure Ice Skate | WEB For ...


Lake Placid Metro Girl?s Adjustable Figure Ice Skate Review

Get out on the ice in Lake Placid?s Metro girls? recreational ice skates. The skates adjust to fit the foot with a push button, and they keep you warm with a soft-touch liner. Their heat-treated, edge-hardened blades make it a breeze to cruise across the ice.

girls ice skates

  • Push button adjustable
  • Woven soft touch lining with form fit liner
  • Heat treated & edge hardened carbon steel blade
  • Water proof sole

Source: http://sports-and-outdoors.orgfree.com/14259

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